TRPM8 menthol cold channel
Selected indexed studies
- Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP(2). (Science, 2022) [PMID:36227998]
- A TRP channel that senses cold stimuli and menthol. (Cell, 2002) [PMID:11893340]
- Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8. (Sci Adv, 2024) [PMID:39093967]
_Worker-drafted node — pending editorial review._
Connections
No connections recorded yet.
Sources
- The role and mechanism of action of menthol in topical analgesic products. (2018) pubmed
- Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP(2). (2022) pubmed
- A TRP channel that senses cold stimuli and menthol. (2002) pubmed
- Mechanisms of sensory adaptation and inhibition of the cold and menthol receptor TRPM8. (2024) pubmed
- Structural Basis of Cold and Menthol Sensing by TRPM8. (2025) pubmed
- TRPM8-driven thermogenesis by menthol: mechanisms of cold injury prevention. (2025) pubmed
- TCAF2 in Pericytes Promotes Colorectal Cancer Liver Metastasis via Inhibiting Cold-Sensing TRPM8 Channel. (2023) pubmed
- Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately. (2024) pubmed
- Evolution of the human cold/menthol receptor, TRPM8. (2019) pubmed
- Structure of the cold- and menthol-sensing ion channel TRPM8. (2018) pubmed