telomerase TERT TERC
Selected indexed studies
- YTHDC1 Orchestrates Telomerase Assembly via Scaffold-Mediated TERT-TERC Interaction. (Aging Cell, 2026) [PMID:41456942]
- TERT and TERC mutations detected in cryptic dyskeratosis congenita suppress telomerase activity. (Int J Lab Hematol, 2020) [PMID:32150348]
- Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells. (Cancer Sci, 2008) [PMID:18482052]
_Worker-drafted node — pending editorial review._
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Sources
- YTHDC1 Orchestrates Telomerase Assembly via Scaffold-Mediated TERT-TERC Interaction. (2026) pubmed
- TERT and TERC mutations detected in cryptic dyskeratosis congenita suppress telomerase activity. (2020) pubmed
- Increased copy number of the TERT and TERC telomerase subunit genes in cancer cells. (2008) pubmed
- Cryo-EM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization. (2025) pubmed
- KLF4 regulates TERT expression in alveolar epithelial cells in pulmonary fibrosis. (2022) pubmed
- AGO2 promotes telomerase activity and interaction between the telomerase components TERT and TERC. (2019) pubmed
- Clinical mutations in the TERT and TERC genes coding for telomerase components induced oxidative stress, DNA damage at telomeres and cell apoptosis besides decreased telomerase activity. (2024) pubmed
- Berberine and RNAi-Targeting Telomerase Reverse Transcriptase (TERT) and/or Telomerase RNA Component (TERC) Caused Oxidation in Colorectal Cancer Cell Line, HCT 116: An Integrative Approach using Molecular and Metabolomic Studies. (2024) pubmed
- Targeting telomerase. (2006) pubmed
- HuR regulates telomerase activity through TERC methylation. (2018) pubmed