sirtuin SIRT6 nuclear
Selected indexed studies
- Is nuclear sirtuin SIRT6 a master regulator of immune function? (Am J Physiol Endocrinol Metab, 2021) [PMID:33308014]
- SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease. (J Clin Invest, 2022) [PMID:34793336]
- SIRT6 Protects Smooth Muscle Cells From Senescence and Reduces Atherosclerosis. (Circ Res, 2021) [PMID:33353368]
_Worker-drafted node — pending editorial review._
Connections
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Sources
- SIRT6 Protects Smooth Muscle Cells From Senescence and Reduces Atherosclerosis. (2021) pubmed
- Is nuclear sirtuin SIRT6 a master regulator of immune function? (2021) pubmed
- SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease. (2022) pubmed
- Epithelial SIRT6 governs IL-17A pathogenicity and drives allergic airway inflammation and remodeling. (2023) pubmed
- Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways. (2023) pubmed
- Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation. (2022) pubmed
- Sirt6 Alleviated Liver Fibrosis by Deacetylating Conserved Lysine 54 on Smad2 in Hepatic Stellate Cells. (2021) pubmed
- The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy. (2021) pubmed
- SIRT6 as a key event linking P53 and NRF2 counteracts APAP-induced hepatotoxicity through inhibiting oxidative stress and promoting hepatocyte proliferation. (2021) pubmed
- SIRT6 Lysine-Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE-Cadherin Pathway Regulating Vascular Endothelial Barrier. (2025) pubmed