Rosuvastatin
Rosuvastatin is a prescription medication used to lower cholesterol levels and reduce the risk of heart disease, making it an important tool in managing cardiovascular health.
Indexed studies highlight that rosuvastatin can effectively manage high cholesterol when used alone or with ezetimibe. However, these studies also indicate potential kidney-related side effects such as hematuria and proteinuria. Additionally, beyond its primary function, rosuvastatin may offer other health benefits not directly related to cholesterol levels.
This medication is notably linked to liver toxicity, based on evidence from a cohort study. It's also connected to the management of hypercholesterolemia and cardiovascular disease prevention.
While the research provides valuable insights into rosuvastatin’s effects, the quality of evidence varies, and more studies are needed for comprehensive understanding.
Sources
- Rosuvastatin/Ezetimibe: A Review in Hypercholesterolemia. (PMID:32648167)
- Association of Rosuvastatin Use with Risk of Hematuria and Proteinuria. (PMID:35853713)
- Rosuvastatin: Beyond the cholesterol-lowering effect. (PMID:26930419)
- Rosuvastatin calcium: A comprehensive profile. (PMID:41714071)
- Rosuvastatin--'the super statin'. (PMID:11732211)
- Comparison of rosuvastatin 10 mg plus ezetimibe versus rosuvastatin 20 mg in atherosclerotic cardiovascular disease and type 2 diabetes. (PMID:40341101)
_Worker-drafted node, Hermes writer enrichment, pending editorial review._
Connections
Rosuvastatin is a side effect of
Sources
- Rosuvastatin/Ezetimibe: A Review in Hypercholesterolemia. (2020) pubmed
- Association of Rosuvastatin Use with Risk of Hematuria and Proteinuria. (2022) pubmed
- Rosuvastatin: Beyond the cholesterol-lowering effect. (2016) pubmed
- Rosuvastatin calcium: A comprehensive profile. (2026) pubmed
- Rosuvastatin--'the super statin'. (2001) pubmed
- Comparison of rosuvastatin 10 mg plus ezetimibe versus rosuvastatin 20 mg in atherosclerotic cardiovascular disease and type 2 diabetes. (2025) pubmed
- The pharmacogenetics of rosuvastatin and implications for treatment: a systematic review. (2025) pubmed
- Rhabdomyolysis during concomitant ticagrelor and rosuvastatin: A breast cancer resistance protein-mediated drug interaction? (2023) pubmed
- Comparing the effectiveness of Rosuvastatin and Atorvastatin on changes in LDL, TG and HDL: A systematic review and meta-analysis. (2025) pubmed
- Rosuvastatin pharmacogenetics in African populations. (2018) pubmed