prothrombin complex concentrate
Selected indexed studies
- Efficacy and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists presenting with major bleeding: a randomized, plasma-controlled, phase IIIb study. (Circulation, 2013) [PMID:23935011]
- Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial. (JAMA, 2023) [PMID:36942533]
- Prothrombin complex concentrate in major bleeding associated with DOACs; an updated systematic review and meta-analysis. (J Thromb Thrombolysis, 2021) [PMID:34024021]
_Worker-drafted node — pending editorial review._
Connections
prothrombin complex concentrate is a side effect of
Sources
- Efficacy and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists presenting with major bleeding: a randomized, plasma-controlled, phase IIIb study. (2013) pubmed
- Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial. (2023) pubmed
- Prothrombin complex concentrate in major bleeding associated with DOACs; an updated systematic review and meta-analysis. (2021) pubmed
- Roles of Four-Factor Prothrombin Complex Concentrate in the Management of Critical Bleeding. (2021) pubmed
- Effectiveness of prothrombin complex concentrate for the treatment of bleeding: A systematic review and meta-analysis. (2020) pubmed
- Andexanet alfa or prothrombin complex concentrate for acute reversal of oral factor Xa inhibitors: monitoring of antidote effects. (2024) pubmed
- Fixed-Dose Four-Factor Prothrombin Complex Concentrate for Vitamin K Antagonist Reversal: Does One Dose Fit All? (2019) pubmed
- Immediate Higher-Dose Prothrombin Complex Concentrate Without Fresh Frozen Plasma or Fibrinogen Concentrate for Significant Coagulopathic Cardiac Surgical Field Bleeding. (2022) pubmed
- Prothrombin Complex Concentrate vs Conservative Management in ICH Associated With Direct Oral Anticoagulants. (2024) pubmed
- Four-factor prothrombin complex concentrate use for on-label versus off-label indications: a retrospective cohort study. (2023) pubmed