PPAR-alpha lipid
Selected indexed studies
- ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. (Nat Med, 2011) [PMID:21857651]
- USP28 Serves as a Key Suppressor of Mitochondrial Morphofunctional Defects and Cardiac Dysfunction in the Diabetic Heart. (Circulation, 2024) [PMID:37994595]
- Macrophage-derived lipid agonists of PPAR-α as intrinsic controllers of inflammation. (Crit Rev Biochem Mol Biol, 2016) [PMID:26585314]
_Worker-drafted node — pending editorial review._
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Sources
- ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. (2011) pubmed
- USP28 Serves as a Key Suppressor of Mitochondrial Morphofunctional Defects and Cardiac Dysfunction in the Diabetic Heart. (2024) pubmed
- Macrophage-derived lipid agonists of PPAR-α as intrinsic controllers of inflammation. (2016) pubmed
- PPAR-mediated reduction of lipid accumulation in hepatocytes involves the autophagy-lysosome-mitochondrion axis. (2025) pubmed
- Macrophage angiotensin-converting enzyme reduces atherosclerosis by increasing peroxisome proliferator-activated receptor α and fundamentally changing lipid metabolism. (2023) pubmed
- PPAR-α, a lipid-sensing transcription factor, regulates blood-brain barrier efflux transporter expression. (2017) pubmed
- Roles of the peroxisome proliferator-activated receptors (PPARs) in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). (2023) pubmed
- Trehalose-induced SIRT1/AMPK activation regulates SREBP-1c/PPAR-α to alleviate lipid accumulation in aged liver. (2024) pubmed
- SIRT1 prevents cigarette smoking-induced lung fibroblasts activation by regulating mitochondrial oxidative stress and lipid metabolism. (2022) pubmed
- PPAR-α agonists are still on the rise: an update on clinical and experimental findings. (2017) pubmed