poly-ADP-ribose PARP1 DNA repair
Selected indexed studies
- Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins. (Nucleic Acids Res, 2019) [PMID:30799503]
- PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends. (Cell, 2024) [PMID:38320550]
- Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors. (Cancer Res, 2012) [PMID:23118055]
_Worker-drafted node — pending editorial review._
Connections
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Sources
- Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins. (2019) pubmed
- PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends. (2024) pubmed
- Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors. (2012) pubmed
- Transcription-replication conflicts underlie sensitivity to PARP inhibitors. (2024) pubmed
- XRCC1 prevents toxic PARP1 trapping during DNA base excision repair. (2021) pubmed
- Poly(ADP-ribose) polymerase 1 regulates mitochondrial DNA repair in an NAD-dependent manner. (2021) pubmed
- Poly(ADP-ribose) and carcinogenesis. (2003) pubmed
- Multi-omics landscape and molecular basis of radiation tolerance in a tardigrade. (2024) pubmed
- Poly(ADP-Ribose)-Dependent Chromatin Remodeling in DNA Repair. (2017) pubmed
- EZH2 directly methylates PARP1 and regulates its activity in cancer. (2024) pubmed