Omeprazole (Prilosec)
Omeprazole, sold under the brand name Prilosec, is a medication used to treat conditions caused by excess stomach acid such as gastroesophageal reflux disease (GERD), and it matters because it can significantly improve quality of life for those suffering from these issues. Studies have found that omeprazole effectively controls gastric acid production, though its effectiveness may be slightly lower compared to some other proton pump inhibitors like esomeprazole. Research also indicates a potential link between long-term use of proton pump inhibitors and bone health concerns, although the specific risks related to omeprazole are not fully understood from these studies alone. Common side effects include nausea and headache, as noted in clinical trials. While omeprazole is generally well-tolerated, it's important to be aware that evidence on its long-term effects remains limited, especially regarding bone health impacts.
Sources
- Proton Pump Inhibitors and Bone Health: An Update Narrative Review. (PMID:36142643)
- Comparative effectiveness and tolerability of esomeprazole and omeprazole in gastro-esophageal reflux disease: A systematic review and meta-analysis. (PMID:26329348)
- Pharmacological treatment of gastro-oesophageal reflux in children. (PMID:37635269)
- Esomeprazole. (PMID:10983736)
- Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial. (PMID:11280530)
- Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study. (PMID:14687806)
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Connections
Omeprazole (Prilosec) is a side effect of
Sources
- Proton Pump Inhibitors and Bone Health: An Update Narrative Review. (2022) pubmed
- Comparative effectiveness and tolerability of esomeprazole and omeprazole in gastro-esophageal reflux disease: A systematic review and meta-analysis. (2015) pubmed
- Pharmacological treatment of gastro-oesophageal reflux in children. (2023) pubmed
- Esomeprazole. (2000) pubmed
- Efficacy and safety of esomeprazole compared with omeprazole in GERD patients with erosive esophagitis: a randomized controlled trial. (2001) pubmed
- Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: a five-way crossover study. (2003) pubmed
- An update on drug-drug interactions associated with proton pump inhibitors. (2022) pubmed
- Naproxen/esomeprazole (Vimovo). (2010) pubmed
- Introduction: Biocatalysis in Industry. (2018) pubmed
- Addendum: Dexlansoprazole for GERD. (2022) pubmed