mitochondrial unfolded protein UPRmt
Selected indexed studies
- A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60. (J Clin Invest, 2022) [PMID:35653190]
- The extracellular matrix integrates mitochondrial homeostasis. (Cell, 2024) [PMID:38942015]
- The mitochondrial unfolded protein response inhibits pluripotency acquisition and mesenchymal-to-epithelial transition in somatic cell reprogramming. (Nat Metab, 2025) [PMID:40205158]
_Worker-drafted node — pending editorial review._
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Sources
- A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60. (2022) pubmed
- The extracellular matrix integrates mitochondrial homeostasis. (2024) pubmed
- The mitochondrial unfolded protein response inhibits pluripotency acquisition and mesenchymal-to-epithelial transition in somatic cell reprogramming. (2025) pubmed
- ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response. (2023) pubmed
- Mitochondrial dysfunction in aging. (2023) pubmed
- ATF5-Mediated Mitochondrial Unfolded Protein Response (UPR(mt)) Protects Neurons Against Oxygen-Glucose Deprivation and Cerebral Ischemia. (2024) pubmed
- Sirtuin-3 activates the mitochondrial unfolded protein response and reduces cerebral ischemia/reperfusion injury. (2023) pubmed
- (+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease. (2024) pubmed
- The mitochondrial unfolded protein response: A multitasking giant in the fight against human diseases. (2022) pubmed
- The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling. (2018) pubmed