manogepix
Selected indexed studies
- In vitro activity of manogepix and comparators against infrequently encountered yeast and mold isolates from the SENTRY Surveillance Program (2017-2022). (Antimicrob Agents Chemother, 2024) [PMID:38205999]
- Structural insights into the inhibition mechanism of fungal GWT1 by manogepix. (Nat Commun, 2024) [PMID:39448635]
- Manogepix (APX001A) In Vitro Activity against Candida auris: Head-to-Head Comparison of EUCAST and CLSI MICs. (Antimicrob Agents Chemother, 2020) [PMID:32660998]
_Worker-drafted node — pending editorial review._
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- In vitro activity of manogepix and comparators against infrequently encountered yeast and mold isolates from the SENTRY Surveillance Program (2017-2022). (2024) pubmed
- Structural insights into the inhibition mechanism of fungal GWT1 by manogepix. (2024) pubmed
- Manogepix (APX001A) In Vitro Activity against Candida auris: Head-to-Head Comparison of EUCAST and CLSI MICs. (2020) pubmed
- The combination of manogepix and itraconazole is synergistic and inhibits the growth of Madurella mycetomatis in vitro but not in vivo. (2023) pubmed
- Antibiofilm activity of manogepix, ibrexafungerp, amphotericin B, rezafungin, and caspofungin against Candida spp. biofilms of reference and clinical strains. (2025) pubmed
- TAC1b mutation in Candida auris decreases manogepix susceptibility owing to increased CDR1 expression. (2025) pubmed
- Manogepix (APX001A) Displays Potent In Vitro Activity against Human Pathogenic Yeast, but with an Unexpected Correlation to Fluconazole MICs. (2020) pubmed
- Fosmanogepix: A Review of the First-in-Class Broad Spectrum Agent for the Treatment of Invasive Fungal Infections. (2020) pubmed
- Mutations in transcription factors that confer fluconazole resistance also confer reduced susceptibility to manogepix in Candida auris (Candidozyma auris), Candida albicans, Candida parapsilosis, and Candida glabrata (Nakaseomyces glabratus). (2025) pubmed
- Activities of Manogepix and Comparators against 1,435 Recent Fungal Isolates Collected during an International Surveillance Program (2020). (2022) pubmed