Lactobacillus rhamnosus GG

Lactobacillus rhamnosus GG is a probiotic bacterium that has been studied for its potential health benefits over three decades. Research indicates it can help maintain gut health and may support immune function, particularly in children. Studies also show promising results in using Lactobacillus rhamnosus GG to ameliorate osteoporosis by balancing certain immune responses and altering gut microbiota structure. Additionally, this bacterium has been found to promote wound healing through the release of extracellular vesicles and can protect against liver injury induced by certain drugs.

This microorganism is notably connected to digestive health, immune system support, and bone density maintenance. Its effects on gut microbiota balance suggest it could be beneficial for those with gastrointestinal issues or weakened immunity. However, while the evidence supports its benefits in these areas, more extensive human trials are needed to fully understand its long-term impacts and optimal use in various conditions.

Sources

• Thirty Years of Lactobacillus rhamnosus GG: A Review. (PMID:30741841)
• Lactobacillus rhamnosus GG ameliorates osteoporosis in ovariectomized rats by regulating the Th17/Treg balance and gut microbiota structure. (PMID:36941563)
• Approach to probiotics in pediatrics: the role of Lactobacillus rhamnosus GG. (PMID:35068121)
• Towards a better understanding of Lactobacillus rhamnosus GG--host interactions. (PMID:25186587)
• Lactobacillus rhamnosus GG-derived extracellular vesicles promote wound healing via miR-21-5p-mediated re-epithelization and angiogenesis. (PMID:39427198)
• Lactobacillus rhamnosus GG ameliorates triptolide-induced liver injury through modulation of the bile acid-FXR axis. (PMID:38908615)

_Worker-drafted node, Hermes writer enrichment, pending editorial review._