ketogenesis HMG-CoA lyase
Selected indexed studies
- HMG-CoA Lyase Deficiency: A Retrospective Study of 62 Saudi Patients. (Front Genet, 2022) [PMID:35646072]
- More Than One HMG-CoA Lyase: The Classical Mitochondrial Enzyme Plus the Peroxisomal and the Cytosolic Ones. (Int J Mol Sci, 2019) [PMID:31817290]
- Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression. (EMBO J, 2022) [PMID:35307861]
_Worker-drafted node — pending editorial review._
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Sources
- HMG-CoA Lyase Deficiency: A Retrospective Study of 62 Saudi Patients. (2022) pubmed
- More Than One HMG-CoA Lyase: The Classical Mitochondrial Enzyme Plus the Peroxisomal and the Cytosolic Ones. (2019) pubmed
- Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression. (2022) pubmed
- HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility. (2023) pubmed
- Molecular genetics of HMG-CoA lyase deficiency. (2007) pubmed
- Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes. (2010) pubmed
- Perioperative Anesthetic Considerations in HMG-CoA Lyase Deficiency: Case Report and Literature Review. (2025) pubmed
- HMG-CoA synthase 1 is a synthetic lethal partner of BRAF(V600E) in human cancers. (2017) pubmed
- Characterization of splice variants of the genes encoding human mitochondrial HMG-CoA lyase and HMG-CoA synthase, the main enzymes of the ketogenesis pathway. (2012) pubmed
- Differential HMG-CoA lyase expression in human tissues provides clues about 3-hydroxy-3-methylglutaric aciduria. (2010) pubmed