JAK-STAT1
Selected indexed studies
- Age-associated B cells contribute to the pathogenesis of rheumatoid arthritis by inducing activation of fibroblast-like synoviocytes via TNF-α-mediated ERK1/2 and JAK-STAT1 pathways. (Ann Rheum Dis, 2022) [PMID:35760450]
- Interferon-γ induces salivary gland epithelial cell ferroptosis in Sjogren's syndrome via JAK/STAT1-mediated inhibition of system Xc(). (Free Radic Biol Med, 2023) [PMID:37286044]
- JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia. (EMBO Mol Med, 2024) [PMID:39521937]
_Worker-drafted node — pending editorial review._
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- Age-associated B cells contribute to the pathogenesis of rheumatoid arthritis by inducing activation of fibroblast-like synoviocytes via TNF-α-mediated ERK1/2 and JAK-STAT1 pathways. (2022) pubmed
- Interferon-γ induces salivary gland epithelial cell ferroptosis in Sjogren's syndrome via JAK/STAT1-mediated inhibition of system Xc(). (2023) pubmed
- JAK-STAT1 as therapeutic target for EGFR deficiency-associated inflammation and scarring alopecia. (2024) pubmed
- SMYD2-mediated methylation of STAT1 protects against hepatic ischaemia/reperfusion injury by blocking JAK-STAT1 signalling pathways. (2026) pubmed
- Janus Kinase Inhibitors in the Treatment of Vitiligo: A Review. (2021) pubmed
- Exosomal Biglycan promotes gastric cancer progression via M2 polarization and CXCL10-mediated JAK/STAT1 activation. (2025) pubmed
- Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes. (2021) pubmed
- Serine metabolism orchestrates macrophage polarization by regulating the IGF1-p38 axis. (2022) pubmed
- Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses. (2019) pubmed
- The Interaction of the IFNγ/JAK/STAT1 and JAK/STAT3 Signalling Pathways in EGFR-Mutated Lung Adenocarcinoma Cells. (2022) pubmed