homologous recombination BRCA1
Selected indexed studies
- BRCA1/2 signaling and homologous recombination deficiency in breast and ovarian cancer. (Future Oncol, 2021) [PMID:34058833]
- Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51. (Nat Commun, 2023) [PMID:37973845]
- BRCAness, Homologous Recombination Deficiencies, and Synthetic Lethality. (Cancer Res, 2023) [PMID:37057596]
_Worker-drafted node — pending editorial review._
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Sources
- BRCA1/2 signaling and homologous recombination deficiency in breast and ovarian cancer. (2021) pubmed
- Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51. (2023) pubmed
- BRCAness, Homologous Recombination Deficiencies, and Synthetic Lethality. (2023) pubmed
- Homologous Recombination Defects and Mutations in DNA Damage Response (DDR) Genes Besides BRCA1 and BRCA2 as Breast Cancer Biomarkers for PARP Inhibitors and Other DDR Targeting Therapies. (2023) pubmed
- BRCA1/2 and homologous recombination repair alterations in high- and low-volume metastatic hormone-sensitive prostate cancer: prevalence and impact on outcomes. (2025) pubmed
- BRCA1 Mutations in Cancer: Coordinating Deficiencies in Homologous Recombination with Tumorigenesis. (2020) pubmed
- Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors. (2025) pubmed
- Treatment patterns and outcomes in metastatic castration-resistant prostate cancer patients with and without somatic or germline alterations in homologous recombination repair genes. (2024) pubmed
- "Bridging the DNA divide": Understanding the interplay between replication- gaps and homologous recombination proteins RAD51 and BRCA1/2. (2024) pubmed
- BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing. (2017) pubmed