GDF15 mitokine
Selected indexed studies
- GDF15, an emerging key player in human aging. (Ageing Res Rev, 2022) [PMID:35051643]
- Mitochondrial stress and mitokines in aging. (Aging Cell, 2023) [PMID:36642986]
- ATF4-dependent and independent mitokine secretion from OPA1 deficient skeletal muscle in mice is sexually dimorphic. (Front Endocrinol (Lausanne), 2024) [PMID:39381436]
_Worker-drafted node — pending editorial review._
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Sources
- GDF15, an emerging key player in human aging. (2022) pubmed
- Mitochondrial stress and mitokines in aging. (2023) pubmed
- ATF4-dependent and independent mitokine secretion from OPA1 deficient skeletal muscle in mice is sexually dimorphic. (2024) pubmed
- Mitochondrial dysfunction decreases cisplatin sensitivity in gastric cancer cells through upregulation of integrated stress response and mitokine GDF15. (2024) pubmed
- Impact of physical activity on physical function, mitochondrial energetics, ROS production, and Ca(2+) handling across the adult lifespan in men. (2025) pubmed
- Coping With Stress: The Mitokine GDF-15 as a Biomarker of COVID-19 Severity. (2022) pubmed
- Different roles of circulating and intramuscular GDF15 as markers of skeletal muscle health. (2024) pubmed
- Downregulation of PLIN2 in human dermal fibroblasts impairs mitochondrial function in an age-dependent fashion and induces cell senescence via GDF15. (2024) pubmed
- Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity. (2022) pubmed
- Circulating total and H-specific GDF15 levels are elevated in subjects with MASLD but not in hyperlipidemic but otherwise metabolically healthy subjects with obesity. (2024) pubmed