cytochrome P450 CYP2C9
Selected indexed studies
- Cytochrome P450: genotype to phenotype. (Xenobiotica, 2020) [PMID:31411087]
- The Cytochrome P450 Slow Metabolizers CYP2C92 and CYP2C93 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production. (Cancer Res, 2018) [PMID:30012669]
- Variability in human drug metabolizing cytochrome P450 CYP2C9, CYP2C19 and CYP3A5 activities caused by genetic variations in cytochrome P450 oxidoreductase. (Biochem Biophys Res Commun, 2019) [PMID:31128914]
_Worker-drafted node — pending editorial review._
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Sources
- Cytochrome P450: genotype to phenotype. (2020) pubmed
- Variability in human drug metabolizing cytochrome P450 CYP2C9, CYP2C19 and CYP3A5 activities caused by genetic variations in cytochrome P450 oxidoreductase. (2019) pubmed
- Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and CYP3A4) enzymes and organic anion transporting polypeptide (OATP1B1 and OATP2B1) transporters. (2023) pubmed
- The Cytochrome P450 Slow Metabolizers CYP2C9*2 and CYP2C9*3 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production. (2018) pubmed
- Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin. (1999) pubmed
- Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines. (2012) pubmed
- The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH:cytochrome P450 oxidoreductase. (1997) pubmed
- The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement. (2001) pubmed
- Induction of cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but not of CYP2C9, CYP2C19, multidrug resistance (MDR-1) and multidrug resistance associated protein (MRP-1) by prototypical inducers in human hepatocytes. (2000) pubmed
- Metabolism of sesamin by cytochrome P450 in human liver microsomes. (2010) pubmed