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Pathway

cellular senescence p16 p21

Selected indexed studies

  • Shear stress-induced cellular senescence blunts liver regeneration through Notch-sirtuin 1-P21/P16 axis. (Hepatology, 2022) [PMID:34687050]
  • Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration. (Autophagy, 2025) [PMID:39988732]
  • The role of p21 in cellular senescence and aging-related diseases. (Mol Cells, 2024) [PMID:39304134]

_Worker-drafted node — pending editorial review._

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