Ashwagandha (KSM-66)

Ashwagandha (KSM-66) is a supplement derived from the root of Withania somnifera and is used to support various aspects of health, including cognitive function and stress management.

Research indicates that Ashwagandha can have neuroprotective effects, which may help protect against cognitive decline. Studies also show it has potential benefits for hair health and could be safe for use during pregnancy. Additionally, there are findings suggesting it might improve cardiorespiratory endurance in athletic adults. Investigations into its safety reveal no significant adverse effects after repeated dosing over ninety days.

Ashwagandha is notably linked to reducing inflammation and oxidative stress, which can contribute to overall health maintenance. It also appears to support better sleep quality, an important factor for general well-being.

While the evidence supports various benefits of Ashwagandha, more extensive research is needed to fully establish its effects across different populations.

Sources

• Neuroprotective effects of Withania somnifera in the SH-SY5Y Parkinson cell model. (PMID:34765761)
• Ninety-day repeated dose toxicity of Ashwagandha (Withania somnifera) root extract in Wistar rats. (PMID:37711361)
• Effects of Withania somnifera root extract serum application on hair health in healthy adults: A prospective, double-blind, randomized, parallel, placebo-controlled study. (PMID:38006746)
• Efficacy and safety of Ashwagandha (Withania somnifera) root extract in pregnant women: a prospective, randomized, comparative, open-label, 12-week study. (PMID:41767760)
• [Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults.](https://pubmed.ncbi.nlm.nih.gov/26730141/) (PMID:26730141)

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